GRB2 Rabbit Monoclonal Antibody

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Catalog Number:MABN86265
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human GRB2
Reactivity:Human, Mouse, Rat
Applications:WB 1:1000-1:2000,IHC 1:50-1:200,ICC/IF 1:100-1:200,IP 1:20-1:50
Molecular Weight:Calculated MW:25 kDa; Observed MW:25 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ASH; Grb3-3; MST084; NCKAP2; MSTP084; EGFRBP-GRB2

Applications

WB 1:1000-1:2000,IHC 1:50-1:200,ICC/IF 1:100-1:200,IP 1:20-1:50

Immunogen

A synthetic peptide of human GRB2

Target Background

The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms:ASH; Grb3-3; MST084; NCKAP2; MSTP084; EGFRBP-GRB2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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