Immunological Sciences

GRF01776

Recombinant Rat HGF stimulates cell proliferation of the Mv.1.lu cells. The ED50 for this effect is 1.6-6.2 ng/mL, corresponding to a specific activity of 1.6×105~6.3×105 units/mg.

Recombinant Rat HGF stimulates cell proliferation of the Mv.1.lu cells. The ED50 for this effect is 1.6-6.2 ng/mL, corresponding to a specific activity of 1.6×105~6.3×105 units/mg.

Catalog Number:GRF01776
Size:20 ug
Form:lyophilized
Synonyms:HPTA；Hepatocyte growth factor；HGF
Species:HEK293 cells
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Recombinant Rat Hepatocyte growth factor/HGF Protein

Target Background

Hepatocyte growth factor/scatter factor (HGF/SF) is a paracrine cellular growth, motility and morphogenicfactor. It belongs to the peptidase S1 family and Plasminogen subfamily, contains 4 kringle domains, 1 PANdomain and 1 peptidase S1 domain. HGF regulates cell growth, cell motility, and morphogenesis by activatinga tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. HGF is secreted bymesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability tostimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis,and tissue regeneration.

Synonyms:HPTA；Hepatocyte growth factor；HGF

Storage

Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.

Recombinant Rat HGF stimulates cell proliferation of the Mv.1.lu cells. The ED50 for this effect is 1.6-6.2 ng/mL, corresponding to a specific activity of 1.6×105~6.3×105 units/mg.

Recombinant Rat Hepatocyte growth factor/HGF Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 80-100 kDa.

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