Immunological Sciences

GRIA3 Mouse Monoclonal Antibody

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Catalog Number:MABN81008
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human GRIA3 expressed in E. Coli.
Reactivity:Human
Applications:IHC 1:200-1:1000,ELISA 1:5000-1:20000
Molecular Weight:101kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:GLUR3; GLURC; GluA3; MRX94; GLUR-C; GLUR-K3

Applications

IHC 1:200-1:1000,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human GRIA3 expressed in E. Coli.

Target Background

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.

Synonyms:GLUR3; GLURC; GluA3; MRX94; GLUR-C; GLUR-K3

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Ascitic fluid containing 0.03% sodium azide.

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