GRK2 Rabbit Monoclonal antibody

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Catalog Number:MABN03015
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human GRK2
Reactivity:Human
Applications:WB 1:500-1:1000,IP 1:20-1:50
Molecular Weight:Calculated MW: 80 kDa; Observed MW: 80 kDa
Purification:Affinity Purified
Form:Liquid
Synonyms:GRK2; BARK1; FLJ16718; BETA-ARK1; ADRBK1

Applications

WB 1:500-1:1000,IP 1:20-1:50

Immunogen

A synthetic peptide of human GRK2

Target Background

GRK2 kinase activity and cellular localization are tightly regulated by interactions with activated receptors, G-beta and G-gamma subunits, adaptor proteins, phospholipids, caveolin and calmodulin, as well as by phosphorylation. PKC phosphorylation enhances GRK2 activity by promoting its membrane localization and by abolishing the inhibitory association of calmodulin.

Synonyms:GRK2; BARK1; FLJ16718; BETA-ARK1; ADRBK1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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