GRK3 Rabbit Monoclonal Antibody

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Catalog Number:MABN86633
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human GRK3
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:200-1:500,ICC/IF 1:20-1:50
Molecular Weight:Calculated MW:80 kDa; Observed MW:80 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:BARK2; ADRBK2

Applications

WB 1:1000-1:5000,IHC 1:200-1:500,ICC/IF 1:20-1:50

Immunogen

A synthetic peptide of human GRK3

Target Background

The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008]

Synonyms:BARK2; ADRBK2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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