Immunological Sciences

GRM5 (6R13) Rabbit Monoclonal Antibody

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Catalog Number:MABN11784
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Metabotropic Glutamate Receptor 5
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:200-1:500,FC 1:10-1:100
Molecular Weight:132kDa
Purification:Affinity purification
Form:Liquid
Synonyms:GPRC1E; GRM5; Metabotropic glutamate receptor 5 precursor; MGLUR5; MGR5;

Applications

WB 1:1000-1:5000,IHC 1:200-1:500,FC 1:10-1:100

Immunogen

A synthetic peptide of human Metabotropic Glutamate Receptor 5

Target Background

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity. G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol- calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.

Synonyms:GPRC1E; GRM5; Metabotropic glutamate receptor 5 precursor; MGLUR5; MGR5;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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