GSK3 alpha Rabbit Monoclonal antibody

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Catalog Number:MABN02064
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human GSK3 alpha
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50
Molecular Weight:Calculated MW: 51 kDa; Observed MW: 51 kDa
Purification:Affinity Purified
Form:Liquid
Synonyms:Serine/threonine-protein kinase GSK3A

Applications

WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50

Immunogen

A synthetic peptide of human GSK3 alpha

Target Background

GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.

Synonyms:Serine/threonine-protein kinase GSK3A

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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