H2AFX Mouse Monoclonal Antibody

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Catalog Number:MABN82932
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human H2AFX expressed in E. Coli.
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:50-1:200,FC 1:200-1:400
Molecular Weight:15.1kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:H2AX; H2A.X; H2A/X

Applications

WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:50-1:200,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human H2AFX expressed in E. Coli.

Target Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Synonyms:H2AX; H2A.X; H2A/X

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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