HBEGF Rabbit Monoclonal Antibody

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Catalog Number:MABN84206
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human HB EGF
Reactivity:Human,Rat
Applications:WB 1:1000-1:2000
Molecular Weight:23 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:DTR; DTS; DTSF; HB-EGF; HBEGF; HEGFL;;HB EGF

Applications

WB 1:1000-1:2000

Immunogen

A synthesized peptide derived from human HB EGF

Target Background

Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

Synonyms:DTR; DTS; DTSF; HB-EGF; HBEGF; HEGFL;;HB EGF

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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