HDAC1 Rabbit Monoclonal Antibody

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Catalog Number:MABN21452
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:A synthetic peptide of human HDAC1
Reactivity:Human,Mouse,Rat,
Applications:WB 1:1000-1:5000,IHC 1:4000-1:10000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200
Molecular Weight:CalcuLated MW:55kD;Observed MW:62kD
Purification:Protein A
Form:Liquid
Synonyms:HDAC1;RPD3L1;Histone deacetylase 1;HD1

Applications

WB 1:1000-1:5000,IHC 1:4000-1:10000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Immunogen

A synthetic peptide of human HDAC1

Target Background

Cell localization:Nucleus.Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008],

Synonyms:HDAC1;RPD3L1;Histone deacetylase 1;HD1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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