Immunological Sciences

HDAC2 Mouse Monoclonal Antibody

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Catalog Number:MABN85051
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG2b
Clone:Monoclonal
Immunogen:Purified recombinant human HDAC2 protein fragments expressed in E.coli.
Reactivity:Human,Mouse,Rat,Monkey
Applications:WB 1:500-1:1000,ICC 1:50-1:200
Molecular Weight:Calculated MW: 55 kDa; Observed MW: 60 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:HDAC2; Histone deacetylase 2; HD2

Applications

WB 1:500-1:1000,ICC 1:50-1:200

Immunogen

Purified recombinant human HDAC2 protein fragments expressed in E.coli.

Target Background

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA.

Synonyms:HDAC2; Histone deacetylase 2; HD2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

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