HDAC3
Western Blot analysis of various cells using HDAC3 Polyclonal Antibody diluted at 1:1000
| Catalog Number: | ABE2500 |
| Conjugate: | Unconjugated |
| Size: | 100ug |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Clone: | POLY |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human HDAC3. AA range:379-428 |
| Reactivity: | Hu,Ms,Rt |
| Applications: | WB,IHC,IF,ELISA |
| Molecular Weight: | 48kD |
| Purification: | Affinity Purified |
| Form: | Liquid |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008],
Applications
WB,IHC,IF,ELISA
Immunogen
The antiserum was produced against synthesized peptide derived from human HDAC3. AA range:379-428
