Immunological Sciences

HDAC3 (3G3) Mouse Monoclonal Antibody

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Catalog Number:MABN03478
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:IgG1
Clone:Monoclonal
Immunogen:A synthetic peptide of human HDAC3
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 49 kDa; Observed MW: 49 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:HDAC3; Histone deacetylase 3; HD3; RPD3-2; SMAP45

Applications

WB 1:500-1:1000

Immunogen

A synthetic peptide of human HDAC3

Target Background

HDAC3 is a nuclear and cytoplasmic protein that deacetylates both histone (H2A, H3, H4) and non-histone substrates (RelA, SRY, p53, MEF2, PCAF and p300/CBP). HDAC3 deacetylase activity is stimulated by interactions with the N-CoR and SMRT co-repressor proteins. Together, these three proteins form a functional complex that represses transcription associated with nuclear hormone receptors and other transcription factors, including Rev-Erb, COUP-TF, DAX1, MAD and Pit-1.

Synonyms:HDAC3; Histone deacetylase 3; HD3; RPD3-2; SMAP45

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

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