Immunological Sciences

HDAC3 Rabbit Monoclonal Antibody

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Catalog Number:MABN87098
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human HDAC3
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:50-1:100,ICC/IF 1:200-1:500,FC 1:20-1:50,IP 1:20-1:50
Molecular Weight:Calculated MW:49 kDa; Observed MW:49 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:HD3; RPD3; RPD3-2

Applications

WB 1:1000-1:5000,IHC 1:50-1:100,ICC/IF 1:200-1:500,FC 1:20-1:50,IP 1:20-1:50

Immunogen

A synthetic peptide of human HDAC3

Target Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]

Synonyms:HD3; RPD3; RPD3-2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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