HDAC8 Rabbit Monoclonal Antibody

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Catalog Number:MABN02077
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human HDAC8
Reactivity:Human
Applications:WB 1:500-1:1000,IP 1:20-1:50
Molecular Weight:Calculated MW: 42 kDa; Observed MW: 42 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:HDAC8; HDACL1; CDA07; Histone deacetylase 8; HD8

Applications

WB 1:500-1:1000,IP 1:20-1:50

Immunogen

A synthetic peptide of human HDAC8

Target Background

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. May play a role in smooth muscle cell contractility.

Synonyms:HDAC8; HDACL1; CDA07; Histone deacetylase 8; HD8

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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