Immunological Sciences

HEI10 Rabbit Polyclonal Antibody

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Catalog Number:ABN11967
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human CCNB1IP1. AA range:201-250
Reactivity:Human,Rat,Mouse
Applications:WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:20000-1:40000
Molecular Weight:32kDa
Purification:Affinity purification
Form:Liquid
Synonyms:CCNB1IP1; C14orf18; HEI10; E3 ubiquitin-protein ligase CCNB1IP1; Cyclin-B1-interacting protein 1; Human enhancer of invasion 10

Applications

WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:20000-1:40000

Immunogen

The antiserum was produced against synthesized peptide derived from human CCNB1IP1. AA range:201-250

Target Background

HEI10 is a member of the E3 ubiquitin ligase family and functions in progression of the cell cycle through G(2)/M.[supplied by OMIM, Apr 2004],function:E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis.,pathway:Protein modification; protein ubiquitination.,PTM:Phosphorylated by CDC2 on serine or threonine residues (in vitro).,PTM:Ubiquitinated; autoubiquitinated.,similarity:Contains 1 RING-type zinc finger.,subcellular location:May associate with segregating chromosomes during metaphase and anaphase.,subunit:Binds CCNB1 and UBE2L3.,tissue specificity:Highly expressed in heart. Detected at intermediate levels in liver and kidney, and at low levels in placenta, brain and lung.,

Synonyms:CCNB1IP1; C14orf18; HEI10; E3 ubiquitin-protein ligase CCNB1IP1; Cyclin-B1-interacting protein 1; Human enhancer of invasion 10

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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