Histone H2A.X (Phospho Ser139) Rabbit Monoclonal Antibody

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Catalog Number:MABN21478
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:A synthetic Phosphorylated peptide corresponding to residues target protein
Reactivity:Human,Mouse,Rat,
Applications:WB 1:1000-1:5000,IHC 1:2000-1:8000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200
Molecular Weight:CalcuLated MW:15kD;Observed MW:15kD
Purification:Protein A
Form:Liquid
Synonyms:H2AFX;H2AX;Histone H2A.x;H2a/x

Applications

WB 1:1000-1:5000,IHC 1:2000-1:8000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Immunogen

A synthetic Phosphorylated peptide corresponding to residues target protein

Target Background

Cell localization:Nucleus.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015],

Synonyms:H2AFX;H2AX;Histone H2A.x;H2a/x

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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