Immunological Sciences

HKLK3 (C234) Mouse Monoclonal Antibody

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Catalog Number:MABN85938
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgM
Clone:Monoclonal
Immunogen:This HKLK3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 220-250 amino acids from human HKLK3.
Reactivity:Human
Applications:WB 1:500-1:2000
Molecular Weight:28.7kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Prostate-specific antigen, PSA, Gamma-seminoprotein, Seminin, Kallikrein-3, P-30 antigen, Semenogelase, KLK3, APS

Applications

WB 1:500-1:2000

Immunogen

This HKLK3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 220-250 amino acids from human HKLK3.

Target Background

Kallikreins are a subgroup of serine proteases havingdiverse physiological functions. Growing evidence suggests thatmany kallikreins are implicated in carcinogenesis and some havepotential as novel cancer and other disease biomarkers. This geneis one of the fifteen kallikrein subfamily members located in acluster on chromosome 19. Its protein product is a protease presentin seminal plasma. It is thought to function normally in theliquefaction of seminal coagulum, presumably by hydrolysis of thehigh molecular mass seminal vesicle protein. Serum level of thisprotein, called PSA in the clinical setting, is useful in thediagnosis and monitoring of prostatic carcinoma. Alternate splicingof this gene generates several transcript variants encodingdifferent isoforms.

Synonyms:Prostate-specific antigen, PSA, Gamma-seminoprotein, Seminin, Kallikrein-3, P-30 antigen, Semenogelase, KLK3, APS

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

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