Immunological Sciences

HLA DMB (14D11) Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN12079
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human HLA DMB
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:100-1:200,ICC/IF 1:100-1:500
Molecular Weight:29kDa
Purification:Affinity purification
Form:Liquid
Synonyms:DMB; RING7;

Applications

WB 1:1000-1:5000,IHC 1:100-1:200,ICC/IF 1:100-1:500

Immunogen

A synthetic peptide of human HLA DMB

Target Background

HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. Plays a critical role in catalyzing the release of class II- associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.

Synonyms:DMB; RING7;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

No documents available.