Immunological Sciences

HMG-17 Rabbit Polyclonal Antibody

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Catalog Number:ABN12102
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human HMG17. AA range:1-50
Reactivity:Human,Mouse,Rat
Applications:IHC 1:100-1:300,ICC/IF 1:200-1:1000,ELISA 1:20000-1:40000
Molecular Weight:15-17kDa
Purification:Affinity purification
Form:Liquid
Synonyms:HMGN2; HMG17; Non-histone chromosomal protein HMG-17; High mobility group nucleosome-binding domain-containing protein 2

Applications

IHC 1:100-1:300,ICC/IF 1:200-1:1000,ELISA 1:20000-1:40000

Immunogen

The antiserum was produced against synthesized peptide derived from human HMG17. AA range:1-50

Target Background

high mobility group nucleosomal binding domain 2(HMGN2) Homo sapiens The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi. [provided by RefSeq, Oct 2014],function:Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation.,mass spectrometry: PubMed:10739259,PTM:Phosphorylation favors cytoplasmic localization.,similarity:Belongs to the HMGN family.,subcellular location:Cytoplasmic enrichment upon phosphorylation.,

Synonyms:HMGN2; HMG17; Non-histone chromosomal protein HMG-17; High mobility group nucleosome-binding domain-containing protein 2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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