Immunological Sciences

HMG2 Mouse Monoclonal Antibody

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Catalog Number:MABN85934
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG2b
Clone:Monoclonal
Immunogen:This HMG2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from human HMG2.
Reactivity:Human
Applications:WB 1:500-1:8000
Molecular Weight:11.8kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:High mobility group protein HMGI-C, High mobility group AT-hook protein 2, HMGA2, HMGIC

Applications

WB 1:500-1:8000

Immunogen

This HMG2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from human HMG2.

Target Background

This gene encodes a protein that belongs to thenon-histone chromosomal high mobility group (HMG) protein family.HMG proteins function as architectural factors and are essentialcomponents of the enhancesome. This protein contains structuralDNA-binding domains and may act as a transcriptional regulatingfactor. Identification of the deletion, amplification, andrearrangement of this gene that are associated with myxoidliposarcoma suggests a role in adipogenesis and mesenchymaldifferentiation. A gene knock out study of the mouse counterpartdemonstrated that this gene is involved in diet-induced obesity.Alternate transcriptional splice variants, encoding differentisoforms, have been characterized.

Synonyms:High mobility group protein HMGI-C, High mobility group AT-hook protein 2, HMGA2, HMGIC

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

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