Immunological Sciences

HMGA2 Rabbit Monoclonal Antibody

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Catalog Number:MABN86428
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human HMGA2
Reactivity:Human
Applications:WB 1:500-1:2000,ICC/IF 1:200-1:500,FC 1:200-1:500,IP 1:20-1:50
Molecular Weight:Calculated MW:12 kDa; Observed MW:18 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:BABL; LIPO; HMGIC; HMGI-C; STQTL9

Applications

WB 1:500-1:2000,ICC/IF 1:200-1:500,FC 1:200-1:500,IP 1:20-1:50

Immunogen

A synthetic peptide of human HMGA2

Target Background

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Synonyms:BABL; LIPO; HMGIC; HMGI-C; STQTL9

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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