HMGB1 Rabbit Monoclonal antibody

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Catalog Number:MABN03744
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human HMGB1
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,IHC 1:50-1:100
Molecular Weight:Calculated MW: 25 kDa; Observed MW: 25 kDa
Purification:Affinity Purified
Form:Liquid
Synonyms:HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1

Applications

WB 1:500-1:1000,IHC 1:50-1:100

Immunogen

A synthetic peptide of human HMGB1

Target Background

High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFκB family, ATF-2 and c-Jun to activate transcription.

Synonyms:HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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