Immunological Sciences

HMGCL Rabbit Monoclonal Antibody

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Catalog Number:MABN84083
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human HMGCL
Reactivity:Human
Applications:WB 1:1000-1:2000,IHC 1:100-1:200
Molecular Weight:Calculated MW: 34 kDa ; Observed MW: 30 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:HMG CoA lyase; HMGCL; Hydroxymethylglutaricaciduria; MS725;;HMGCL

Applications

WB 1:1000-1:2000,IHC 1:100-1:200

Immunogen

A synthesized peptide derived from human HMGCL

Target Background

Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

Synonyms:HMG CoA lyase; HMGCL; Hydroxymethylglutaricaciduria; MS725;;HMGCL

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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