Immunological Sciences

HMGCS2 Rabbit Monoclonal Antibody

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Catalog Number:MABN86662
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human HMGCS2
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:50-1:200
Molecular Weight:Calculated MW:57 kDa; Observed MW:57 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:3-hydroxy-3-methylglutaryl coenzyme A synthase

Applications

WB 1:1000-1:5000,IHC 1:50-1:200

Immunogen

A synthetic peptide of human HMGCS2

Target Background

The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]

Synonyms:3-hydroxy-3-methylglutaryl coenzyme A synthase

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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