HN1 Rabbit Monoclonal Antibody

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Catalog Number:MABN83752
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human JPT1
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000,ICC 1:50-1:200,FC 1:20-1:100
Molecular Weight:Calculated MW: 16 kDa ; Observed MW: 21 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ARM2; HN1; HN1A;;JPT1

Applications

WB 1:1000-1:2000,ICC 1:50-1:200,FC 1:20-1:100

Immunogen

A synthesized peptide derived from human JPT1

Target Background

Modulates negatively AKT-mediated GSK3B signaling.Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions.

Synonyms:ARM2; HN1; HN1A;;JPT1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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