HNF-4-alpha Rabbit Monoclonal Antibody

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Catalog Number:MABN86615
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human HNF-4-alpha
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:200-1:500,ICC/IF 1:100-1:200,FC 1:50-1:100
Molecular Weight:Calculated MW:53 kDa; Observed MW:53 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:TCF; HNF4; MODY; FRTS4; MODY1; NR2A1; TCF14; HNF4a7; HNF4a8; HNF4a9; NR2A21; HNF4alpha

Applications

WB 1:500-1:2000,IHC 1:200-1:500,ICC/IF 1:100-1:200,FC 1:50-1:100

Immunogen

A synthetic peptide of human HNF-4-alpha

Target Background

The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012]

Synonyms:TCF; HNF4; MODY; FRTS4; MODY1; NR2A1; TCF14; HNF4a7; HNF4a8; HNF4a9; NR2A21; HNF4alpha

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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