Immunological Sciences

HNF1A Rabbit Monoclonal Antibody

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Catalog Number:MABN87692
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human HNF1A
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:200-1:2000,ICC/IF 1:500-1:1000,FC 1:200-1:500
Molecular Weight:Calculated MW:67 kDa; Observed MW:81 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:HNF1; LFB1; TCF1; MODY3; TCF-1; HNF-1A; IDDM20

Applications

WB 1:500-1:2000,IHC 1:200-1:2000,ICC/IF 1:500-1:1000,FC 1:200-1:500

Immunogen

Recombinant protein of human HNF1A

Target Background

The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]

Synonyms:HNF1; LFB1; TCF1; MODY3; TCF-1; HNF-1A; IDDM20

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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