hnRNP K Rabbit Monoclonal Antibody

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Catalog Number:MABN85666
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human hnRNP K
Reactivity:Human,Mouse,Rat,Hamster
Applications:WB 1:500-1:1000,IHC 1:50-1:100,ICC 1:50-1:200,IP 1:10-1:20
Molecular Weight:Calculated MW: 51 kDa; Observed MW: 58 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:HNRNPK; HNRPK; Heterogeneous nuclear ribonucleoprotein K; hnRNP K; Transformation up-regulated nuclear protein; TUNP

Applications

WB 1:500-1:1000,IHC 1:50-1:100,ICC 1:50-1:200,IP 1:10-1:20

Immunogen

A synthetic peptide of human hnRNP K

Target Background

Facilitate pre-mRNA processing and transport of mRNA from the nucleus to cytoplasm. hnRNP K contains three unique structural motifs termed KH domains that bind poly(C) DNA and RNA sequences. Intricate architecture enables hnRNP K to facilitate mRNA biosynthesis, transcriptional regulation, and signal transduction. Research studies have shown that cytoplasmic hnRNP K expression is increased in oral squamous cell carcinoma and pancreatic cancer, and may be a potential prognostic factor.

Synonyms:HNRNPK; HNRPK; Heterogeneous nuclear ribonucleoprotein K; hnRNP K; Transformation up-regulated nuclear protein; TUNP

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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