HP1 gamma Rabbit Polyclonal Antibody

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Catalog Number:ABN00234
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:A synthetic peptide of human HP1 gamma
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,IHC 1:50-1:100,FC 1:50-1:100,IP 1:20-1:50
Molecular Weight:Calculated MW: 21 kDa; Observed MW: 24 kDa
Purification:Affinity Chromatography
Form:Liquid
Synonyms:CBX3; Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein

Applications

WB 1:500-1:1000,IHC 1:50-1:100,FC 1:50-1:100,IP 1:20-1:50

Immunogen

A synthetic peptide of human HP1 gamma

Target Background

Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Synonyms:CBX3; Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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