Immunological Sciences

HP1α Rabbit Monoclonal Antibody

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Catalog Number:MABN21444
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:A synthetic peptide of human HP1 alpha
Reactivity:Human,Mouse,Rat,
Applications:WB 1:1000-1:5000,IHC 1:400-1:2000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200
Molecular Weight:CalcuLated MW:22kD;Observed MW:22kD
Purification:Protein A
Form:Liquid
Synonyms:Chromobox protein homolog 5;Antigen p25;Heterochromatin protein 1 homolog alpha;HP1 alpha;

Applications

WB 1:1000-1:5000,IHC 1:400-1:2000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Immunogen

A synthetic peptide of human HP1 alpha

Target Background

Cell localization:Nucleus.This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],

Synonyms:Chromobox protein homolog 5;Antigen p25;Heterochromatin protein 1 homolog alpha;HP1 alpha;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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