HSD11B1 (17P16) Rabbit Monoclonal Antibody

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Catalog Number:MABN12219
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human HSD11B1
Reactivity:Human
Applications:WB 1:2000-1:20000,IHC 1:200-1:2000,ICC/IF 1:50-1:100,FC 1:20-1:50
Molecular Weight:32kDa
Purification:Affinity purification
Form:Liquid
Synonyms:11-DH; 11-beta-HSD1; HSD11B1; HSD11; HSD11L; 11 beta HSD1;

Applications

WB 1:2000-1:20000,IHC 1:200-1:2000,ICC/IF 1:50-1:100,FC 1:20-1:50

Immunogen

A synthetic peptide of human HSD11B1

Target Background

Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol. Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone (PubMed:10497248). Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7- ketocholesterol to 7-beta-hydroxycholesterol (By similarity).

Synonyms:11-DH; 11-beta-HSD1; HSD11B1; HSD11; HSD11L; 11 beta HSD1;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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