Immunological Sciences

Hsp22 Rabbit Monoclonal Antibody

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Catalog Number:MABN86983
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Hsp22
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:50-1:100,ICC/IF 1:50-1:100
Molecular Weight:Calculated MW:22 kDa; Observed MW:22 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:H11; HMN2; CMT2L; DHMN2; E2IG1; HMN2A; HSP22

Applications

WB 1:1000-1:5000,IHC 1:50-1:100,ICC/IF 1:50-1:100

Immunogen

A synthetic peptide of human Hsp22

Target Background

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]

Synonyms:H11; HMN2; CMT2L; DHMN2; E2IG1; HMN2A; HSP22

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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