HTR3A Mouse Monoclonal Antibody

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Catalog Number:MABN81928
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG2a
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human HTR3A (AA: extra 24-157) expressed in E. Coli.
Reactivity:Human
Applications:IHC 1:200-1:1000,ICC 1:100-1:500,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:55.3kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:HTR3; 5HT3R; 5-HT-3; 5-HT3A; 5-HT3R

Applications

IHC 1:200-1:1000,ICC 1:100-1:500,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human HTR3A (AA: extra 24-157) expressed in E. Coli.

Target Background

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.

Synonyms:HTR3; 5HT3R; 5-HT-3; 5-HT3A; 5-HT3R

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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