Immunological Sciences

HtrA2/Omi Rabbit Monoclonal Antibody

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Catalog Number:MABN86489
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human HtrA2/Omi
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:100-1:200
Molecular Weight:Calculated MW:48 kDa; Observed MW:36 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:OMI; MGCA8; PARK13; PRSS25

Applications

WB 1:1000-1:5000,IHC 1:100-1:200

Immunogen

A synthetic peptide of human HtrA2/Omi

Target Background

This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

Synonyms:OMI; MGCA8; PARK13; PRSS25

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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