Immunological Sciences

IGF1 Receptor Rabbit Monoclonal Antibody

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Catalog Number:MABN21599
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:Recombinant protein of human IGF-I receptor beta
Reactivity:Human,
Applications:WB 1:1000-1:5000,IHC 1:100-1:200,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200
Molecular Weight:CalcuLated MW:154kD;Observed MW:200kD
Purification:Protein A
Form:Liquid
Synonyms:IGF1R;InsuLin-like growth factor 1 receptor;InsuLin-like growth factor I receptor;IGF-I receptor;CD antigen CD221

Applications

WB 1:1000-1:5000,IHC 1:100-1:200,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Immunogen

Recombinant protein of human IGF-I receptor beta

Target Background

Cell localization:Membranous.This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],

Synonyms:IGF1R;InsuLin-like growth factor 1 receptor;InsuLin-like growth factor I receptor;IGF-I receptor;CD antigen CD221

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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