Immunological Sciences

IKB alpha Rabbit Monoclonal Antibody

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Catalog Number:MABN87700
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human IKB alpha
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:200-1:500,ICC/IF 1:100-1:200
Molecular Weight:Calculated MW:36 kDa; Observed MW:39 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:IKBA; MAD-3; NFKBI

Applications

WB 1:1000-1:5000,IHC 1:200-1:500,ICC/IF 1:100-1:200

Immunogen

A synthetic peptide of human IKB alpha

Target Background

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]

Synonyms:IKBA; MAD-3; NFKBI

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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