Immunological Sciences

IL-12A Rabbit Monoclonal Antibody

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Catalog Number:MABN86885
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human IL12A
Reactivity:Human,Mouse
Applications:WB 1:1000-1:5000,IHC 1:200-1:1000,FC 1:100-1:200
Molecular Weight:Calculated MW:25 kDa; Observed MW:35 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:P35; CLMF; NFSK; NKSF1; IL-12A

Applications

WB 1:1000-1:5000,IHC 1:200-1:1000,FC 1:100-1:200

Immunogen

A synthetic peptide of human IL12A

Target Background

This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]

Synonyms:P35; CLMF; NFSK; NKSF1; IL-12A

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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