Immunological Sciences

IL-19 Rabbit Polyclonal Antibody

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Catalog Number:ABN12516
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthetic peptide from human protein at AA range: 51-100
Reactivity:Human,Rat
Applications:WB 1:500-1:2000,IHC 1:50-1:200,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000
Molecular Weight:20kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Interleukin-19 (IL-19;Melanoma differentiation-associated protein-like protein;NG.1)

Applications

WB 1:500-1:2000,IHC 1:50-1:200,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000

Immunogen

Synthetic peptide from human protein at AA range: 51-100

Target Background

The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008],function:May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis.,similarity:Belongs to the IL-10 family.,

Synonyms:Interleukin-19 (IL-19;Melanoma differentiation-associated protein-like protein;NG.1)

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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