IL6 Polyclonal Antibody
Western blot analysis of Hepg2 Hela and A549 cell using IL6 Polyclonal Antibody at dilution of 1:400
| Catalog Number: | AB19453 |
| Conjugate: | Unconjugated |
| Size: | 200μL |
| Concentration: | 1.1 mg/mL |
| Host: | Rabbit |
| Isotype: | IgG |
| Clone: | Polyclonal |
| Immunogen: | Synthetic peptide of human IL6 |
| Reactivity: | Human |
| Applications: | WB 1:500-1:2000 |
| Molecular Weight: | Refer to figures |
| Purification: | Antigen affinity purification |
| Synonyms: | IL6;IFNB2 |
Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells,T-cells,hepatocytes,hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine,a cytokine produced from muscle,and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally,IL-6 is involved in hematopoiesis,bone metabolism,and cancer progression,and has been defined an essential role in directing transition from innate to acquired immunity.
Applications
WB 1:500-1:2000
Immunogen
Synthetic peptide of human IL6