Immunological Sciences

Insulin Degrading Enzyme Mouse Mouse Monoclonal Antibody

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Catalog Number:MABN86155
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:A synthetic peptide of human Insulin degrading enzyme/IDE
Reactivity:Human
Applications:WB 1:1000-1:2000,IHC 1:50-1:300,ICC 1:100-1:200
Molecular Weight:118kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Insulin Degrading Enzyme Mouse

Applications

WB 1:1000-1:2000,IHC 1:50-1:300,ICC 1:100-1:200

Immunogen

A synthetic peptide of human Insulin degrading enzyme/IDE

Target Background

Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.

Synonyms:Insulin Degrading Enzyme Mouse

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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