Insulin Receptor R (13V2) Rabbit Monoclonal Antibody

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Catalog Number:MABN12641
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human IRR
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:50-1:100,IF-P 1:50-1:100
Molecular Weight:144kDa
Purification:Affinity purification
Form:Liquid
Synonyms:INSRR; Insulin receptor related receptor precursor; IR related receptor; IRR; Sirr;

Applications

WB 1:500-1:2000,IHC 1:50-1:100,IF-P 1:50-1:100

Immunogen

A synthetic peptide of human IRR

Target Background

This receptor probably binds an insulin related protein and has a tyrosine-protein kinase activity. It phosphorylates the insulin receptor substrates IRS-1 and IRS-2. Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.

Synonyms:INSRR; Insulin receptor related receptor precursor; IR related receptor; IRR; Sirr;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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