Immunological Sciences

Integrin alpha V Rabbit Monoclonal Antibody

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Catalog Number:MABN87568
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Integrin alpha V
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,FC 1:10-1:100
Molecular Weight:Calculated MW:116 kDa; Observed MW:135, 30 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CD51; MSK8; VNRA; VTNR

Applications

WB 1:1000-1:5000,FC 1:10-1:100

Immunogen

A synthetic peptide of human Integrin alpha V

Target Background

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]

Synonyms:CD51; MSK8; VNRA; VTNR

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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