Immunological Sciences

Integrin β1 (phospho Tyr795) Rabbit Polyclonal Antibody

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Catalog Number:ABN04853
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human ITGB1 around the phosphorylation site of Tyr795. AA range:749-798
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,ELISA 1:20000-1:40000
Molecular Weight:140kDa
Purification:Affinity purification
Form:Liquid
Synonyms:ITGB1; FNRB; MDF2; MSK12; Integrin beta-1; Fibronectin receptor subunit beta; VLA-4 subunit beta; CD antigen CD29

Applications

WB 1:500-1:2000,ELISA 1:20000-1:40000

Immunogen

The antiserum was produced against synthesized peptide derived from human ITGB1 around the phosphorylation site of Tyr795. AA range:749-798

Target Background

CD29 is a 130 kD single chain type I glycoprotein also known as integrin β1, VLA-β chain, or gpIIa. It is broadly expressed on a majority of hematopoietic and non-hematopoietic cells, including leukocytes (although at low level on granulocytes), platelets, fibroblasts, endothelial cells, epithelial cells, and mast cells. CD29 is a member of the integrin family. It is non-covalently associated with integrin α1-α6 chains to form VLA-1 to VLA-6 molecules, respectively. Integrins, which include CD29, bind to several cell surface (e.g. VCAM-1, MadCAM-1) and extracellular matrix molecules. CD29 acts as a fibronectin receptor and is involved in a variety of cell-cell and cell-matrix interactions.

Synonyms:ITGB1; FNRB; MDF2; MSK12; Integrin beta-1; Fibronectin receptor subunit beta; VLA-4 subunit beta; CD antigen CD29

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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