Immunological Sciences

IP Receptor Rabbit Polyclonal Antibody

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Catalog Number:ABN12694
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human Prostacyclin Receptor. AA range:198-247
Reactivity:Human,Rat,Mouse
Applications:WB 1:500-1:2000,IHC 1:50-1:300,ELISA 1:2000-1:20000
Molecular Weight:45kDa
Purification:Affinity purification
Form:Liquid
Synonyms:PTGIR; PRIPR; Prostacyclin receptor; Prostaglandin I2 receptor; PGI receptor; PGI2 receptor; Prostanoid IP receptor

Applications

WB 1:500-1:2000,IHC 1:50-1:300,ELISA 1:2000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human Prostacyclin Receptor. AA range:198-247

Target Background

The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. [provided by RefSeq, Jul 2008],function:Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.,PTM:Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C.,PTM:Palmitoylation of either Cys-308 or Cys-311 is sufficient to maintain functional coupling to G(s) and signaling.,similarity:Belongs to the G-protein coupled receptor 1 family.,

Synonyms:PTGIR; PRIPR; Prostacyclin receptor; Prostaglandin I2 receptor; PGI receptor; PGI2 receptor; Prostanoid IP receptor

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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