IP3R-I rabbit Polyclonal Antibody

Western blot analysis of 293T using IP3R-I antibody. Antibody was diluted at 1:500. Secondary antibody was diluted at 1:20000

Western blot analysis of 293T using IP3R-I antibody. Antibody was diluted at 1:500. Secondary antibody was diluted at 1:20000

Catalog Number:ABE8348
Conjugate:unconjugated
Size:100 ug
Concentration:1 mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthesized peptide derived from IP3R-I . at AA range: 1700-1780
Reactivity:Human;Mouse;Rat
Applications:WB 1:500-2000;IHC-p 1:50-300
Molecular Weight:320kD
Form:liquid
Synonyms:ITPR1; INSP3R1; Inositol 1,4,5-trisphosphate receptor type 1; IP3 receptor isoform 1; IP3R 1; InsP3R1; Type 1 inositol 1,4,5-trisphosphate receptor; Type 1 InsP3 receptor

This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009],

Applications

WB 1:500-2000;IHC-p 1:50-300

Immunogen

Synthesized peptide derived from IP3R-I . at AA range: 1700-1780

Target Background

This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009],

Synonyms:ITPR1; INSP3R1; Inositol 1,4,5-trisphosphate receptor type 1; IP3 receptor isoform 1; IP3R 1; InsP3R1; Type 1 inositol 1,4,5-trisphosphate receptor; Type 1 InsP3 receptor

Storage

-20°C/1 year

Western blot analysis of 293T using IP3R-I antibody. Antibody was diluted at 1:500. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

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