Immunological Sciences

IRS1 (17G5) Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN12758
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human IRS1
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:20-1:50,ICC/IF 1:50-1:200,FC 1:20-1:50
Molecular Weight:132kDa
Purification:Affinity purification
Form:Liquid
Synonyms:HIRS1; Insulin receptor substrate 1; IRS 1; IRS1;

Applications

WB 1:1000-1:5000,IHC 1:20-1:50,ICC/IF 1:50-1:200,FC 1:20-1:50

Immunogen

A synthetic peptide of human IRS1

Target Background

IRS1 is one of the major substrates of the insulin receptor kinase. May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).

Synonyms:HIRS1; Insulin receptor substrate 1; IRS 1; IRS1;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

No documents available.