Immunological Sciences

IRS2 Rabbit Polyclonal Antibody

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Catalog Number:ABN12761
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthetic peptide from human protein at AA range: 660-700
Reactivity:Human,Rat,Mouse
Applications:WB 1:500-1:2000,ELISA 1:10000-1:20000
Molecular Weight:170kDa
Purification:Affinity purification
Form:Liquid
Synonyms:IRS2

Applications

WB 1:500-1:2000,ELISA 1:10000-1:20000

Immunogen

Synthetic peptide from human protein at AA range: 660-700

Target Background

This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq, Jul 2008],function:May mediate the control of various cellular processes by insulin.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 IRS-type PTB domain.,similarity:Contains 1 PH domain.,

Synonyms:IRS2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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