Immunological Sciences

JNK1/3 Rabbit Polyclonal Antibody

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Catalog Number:ABN00131
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,IP 1:20-1:50
Molecular Weight:Calculated MW: 48 kDa; Observed MW: 46,54 kDa
Purification:Affinity Chromatography
Form:Liquid
Synonyms:c-Jun N-terminal kinase 3; FLJ12099; FLJ33785; JNK1; JNK3; JNK3 alpha protein kinase; JNK3A; MAP kinase 10; MAP kinase p49 3F12; MAPK 10; MAPK10

Applications

WB 1:500-1:1000,IP 1:20-1:50

Target Background

The stress-activated protein kinase/Jun-amino-terminal kinase SAPK/JNK is potently and preferentially activated by a variety of environmental stresses including UV and gamma radiation, ceramides, inflammatory cytokines, and in some instances, by growth factors and GPCR agonists. As with the other MAPKs, the core signaling unit is composed of a MAPKKK, typically MEKK1-MEKK4, or by one of the mixed lineage kinases (MLKs), which phosphorylate and activate MKK4/7.

Synonyms:c-Jun N-terminal kinase 3; FLJ12099; FLJ33785; JNK1; JNK3; JNK3 alpha protein kinase; JNK3A; MAP kinase 10; MAP kinase p49 3F12; MAPK 10; MAPK10

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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