KAISO Rabbit Monoclonal Antibody

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Catalog Number:MABN84341
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human KAISO
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000
Molecular Weight:Calculated MW: 74 kDa ; Observed MW: 85 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Kaiso; Zbtb33; ZNF Kaiso; ZNF348;;KAISO

Applications

WB 1:1000-1:2000

Immunogen

A synthesized peptide derived from human KAISO

Target Background

Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters.

Synonyms:Kaiso; Zbtb33; ZNF Kaiso; ZNF348;;KAISO

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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